How to make the diagnosis - Dermatology and aesthetics


Dermatology and aesthetics

Dermatology and aesthetics


Chronic lupus erythematosus Lupus tuberculosis
  • Chronic lupus erythematosus
  • Tuberculous lupus

How to make the diagnosis

A clinical examination of the lesions is required; after doing a skin biopsy, it is possible to perform a histological examination of the tissues, which is able to reveal cellular anomalies between the dermis and the epidermis.

The disease does not evolve in a single moment, but progresses in successive waves, which are usually caused by new exposures to the sun.

How to cure it

To treat lupus erythematosus it is necessary to take locally-acting dermocorticosteroids, to be applied by massaging the affected area or by bandaging. Very thickened lesions can be treated with cryosurgery or with the carbon dioxide laser. Many times, however, a single treatment is not enough and general therapy is necessary, which is based on the oral administration of antimalarials or, if these prove to be insufficient, of sulphones, retinoids and thalidomide.

In order to avoid the appearance of chronic lupus erythematosus, it is important not to expose yourself to the sun and always protect yourself from the sun's rays by using creams with total protection.

Systemic lupus erythematosus

Systemic lupus erythematosus (SLE) is an autoimmune inflammatory disease that affects many organs. It is part of systemic diseases (known in the past as connective tissue or collagenosis) and affects women in particular, especially those between 20 and 30 years of age. The factors at the origin of this pathology are manifold but, among these, what has a greater weight is certainly the genetic predisposition: it occurs more frequently, in fact, in subjects carrying the HLA alleles (Human-Leucocyte Antigen, human leukocyte antigen) DR2 and DR3 and in those suffering from congenital deficiency of the C2 or C4 fractions of the complement (i.e. the enzyme system involved in the immune response through the destruction of antigens).

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